There are an ever-increasing and disturbing number of young people claiming their sex lives have been permanently ruined from taking the acne drug, isotretinoin , commonly referred to by its former brand-name, Accutane. Often these affected young men and women, many in their teens and early 20s, cannot overcome their embarrassment to report sexual side effects while taking the drug. Or they continue to expect those side effects to abate after cessation of the drug. Sometimes, they discontinue isotretinoin early because of sexual problems only to find that the problems get worse and persist indefinitely after taking the last pill. Sexual dysfunction has been my lot in life since taking Accutane over 14 years ago, and as noted, I am far from alone. After going on treatment many people get mild-to-debilitating anhedonia, anxiety and fatigue. The sexual symptoms may initially be relatively mild. The problem can then significantly and rapidly worsen when isotretinoin is stopped. Others have noted that it gets gradually worse on treatment and then continues to worsen when treatment is stopped.


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